Quinolines and derivatives

Sigma Aldrich Fine Chemicals Biosciences 8-Hydroxyquinoline crystalline | 148-24-3 | MFCD00006807 | 25G

8-Hydroxyquinoline crystalline | Purity: 98.5-101.5% | Mol Wt: 145.16 | 148-24-3 | MFCD00006807 | 25G

Encompass Procurement Services
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
Learn More

Medchemexpress LLC Lobeglitazone (sulfate) | 763108-62-9 | MFCD28502044 | 99.6% | 578.61 g·mol⁻¹ | C24H26N4O9S2 | 10 MG

Small and Specialty Supplier Partner
Small and/or specialty supplier based on Federal laws and SBA requirements.
Learn More

Lobeglitazone sulfate is a thiazolidinedione-class small molecule used for research as a peroxisome proliferator-activated receptor (PPAR) agonist. It has reported activity on PPARγ (EC50 ≈ 137.4 nM) and PPARα (EC50 ≈ 546.3 nM) and is applied in preclinical studies of metabolic, inflammatory, fibrotic, and atherosclerotic pathways. Follow the product SDS for handling and storage instructions.

• Acts as a PPARγ and PPARα agonist with published EC50 values.
• Supports studies of anti-diabetic, anti-inflammatory, and anti-fibrotic mechanisms.
• High purity suitable for biochemical and cellular assays.
• Provided as a sulfate salt to aid solubility in experimental media.
• Stable under recommended storage; consult SDS for solvent storage conditions.
• Supplied in small quantities appropriate for research workflows.

Encompass Procurement Services
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
Learn More

Accela Chembio Inc 2 | 8-quinolinediol | 25g | 15450-76-7 | MFCD00216696 | 97+% | Shelf Life: 1260 Days | Light Sensitive

Small and Specialty Supplier Partner
Small and/or specialty supplier based on Federal laws and SBA requirements.
Learn More

2 | 8-quinolinediol | 25g | 15450-76-7 | MFCD00216696 | 97+% | Shelf Life: 1260 Days | Light Sensitive

Encompass Procurement Services
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
Learn More

eMolecules​ 4-Chloro-6-hydroxyquinoline | 148018-29-5 | MFCD00456102 | 250mg

Ambeed | 4-Chloro-6-hydroxyquinoline | 250mg | 490556726 | A352245 | | 148018-29-5 | MFCD00456102 | 179.600 | C9H6ClNO

If you are unable to find the chemical you are looking for, make sure you are logged into your fishersci.com account and click on the following link:
eMolecules Building Block Tool

Encompass Procurement Services
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
Learn More

Selleck Chemical LLC Leupeptin Hemisulfate

Leupeptin Hemisulfate is a reversible inhibitor of serine and cysteine proteases It inhibits cathepsin B (Ki 6 nM) calpain (Ki 10 nM) trypsin (Ki 35 nM) plasmin (Ki 3 4 M) and kallikrein (Ki 19 M) and has no effect against chymotrypsin elastase renin or pepsin

Encompass Procurement Services
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
Learn More

TARGETMOL CHEMICALS INC RU.521 10MG

Small and Specialty Supplier Partner
Small and/or specialty supplier based on Federal laws and SBA requirements.
Learn More

Also available in 1 mg 2 mg 5 mg 25 mg 50 mg 100 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. RU.521 (RU3205217) is a potent dsDNA inhibitor (IC50 700 nM) inhibition of the dsDNA pathway by RU.521 requires the presence of cGAS. purity: 99%

Encompass Procurement Services
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
Learn More

Medchemexpress LLC m-PEG7-amine | 170572-38-0 | MFCD13184965 | 98.0% | 339.43 g/mol | C15H33NO7 | 5 G

Small and Specialty Supplier Partner
Small and/or specialty supplier based on Federal laws and SBA requirements.
Learn More

m-PEG7-Amine is a methoxy-terminated polyethylene glycol (PEG) linker bearing a terminal primary amine. It is used as a PROTAC linker and as a cleavable ADC linker for antibody-drug conjugation and other bioconjugation applications. The reagent provides a flexible, hydrophilic spacer suitable for linker chemistry in targeted degraders and conjugates.

• Methoxy-terminated PEG with seven ethylene glycol units.
• Terminal primary amine for facile coupling to carboxylates and activated esters.
• Molecular weight 339.43 g/mol and CAS 170572-38-0.
• Suitable for use as a PROTAC linker and a cleavable ADC linker.
• Hydrophilic spacer that improves solubility and reduces aggregation in conjugates.

Encompass Procurement Services
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
Learn More

Medchemexpress LLC Mpeg-amine (MW 1000) | 80506-64-5 | 99.19% | (C2H4O)nC3H9NO | 100 MG

Small and Specialty Supplier Partner
Small and/or specialty supplier based on Federal laws and SBA requirements.
Learn More

m-PEG-NH2 (MW 1000) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.

• PEG-based PROTAC linker
• Used in the synthesis of PROTACs
• Facilitates degradation of target proteins
• Utilizes the ubiquitin-proteasome system

Encompass Procurement Services
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
Learn More

Medchemexpress LLC Azido-PEG1-amine | 464190-91-8 | ≥98.0% | C4H10N4O | 100 MG

Small and Specialty Supplier Partner
Small and/or specialty supplier based on Federal laws and SBA requirements.
Learn More

Azido-PEG1-amine is a PEG-based PROTAC linker designed for the synthesis of PROTACs. It functions as a click chemistry reagent due to its Azide group, enabling copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions with alkyne-containing molecules and strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules possessing DBCO or BCN groups. PROTACs utilize two ligands connected by a linker to target an E3 ubiquitin ligase and a protein of interest, facilitating selective degradation via the intracellular ubiquitin-proteasome system.

• PEG-based PROTAC linker
• Functions as a click chemistry reagent
• Enables copper-catalyzed azide-alkyne cycloaddition (CuAAc)
• Participates in strain-promoted alkyne-azide cycloaddition (SPAAC)
• Utilized in PROTAC synthesis
• Relevant for cancer targeted therapy

Encompass Procurement Services
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
Learn More